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An endopeptidase inhibitor is a drug that inhibits one or more endopeptidase enzymes. ==Examples of endopeptidase inhibitors== Some examples of endopeptidase inhibitors include the following: * Neprilysin inhibitors * * Selective neprilysin inhibitors * * * Candoxatril - prodrug to candoxatrilat * * * Candoxatrilat - active metabolite of candoxatril * * * Dexecadotril (retorphan) - (''R'')-enantiomer of racecadotril; prodrug to (''R'')-thiorphan * * * Ecadotril (sinorphan) - (''S'')-enantiomer of racecadotril; prodrug to (''S'')-thiorphan * * * Racecadotril (acetorphan) - racemic form of dexecadotril and ecadotril; prodrug to thiorphan * * * Sacubitril - prodrug to sacubitrilat * * * Sacubitrilat - active metabolite of sacubitril * * * Thiorphan - active metabolite of racecadotril * * * UK-414,495 * * Non-selective neprilysin inhibitors * * * Aladotril - also inhibits angiotensin converting enzyme (ACE) (an exopeptidase) * * * Alatriopril - also inhibits ACE * * * Daglutril - also inhibits endothelin converting enzyme (ECE) (an exopeptidase) * * * Fasidotril - also inhibits ACE * * * Gemopatrilat - also inhibits ACE * * * Ilepatril - also inhibits ACE * * * Ketalorphan - also inhibits APN, ACE, and dipeptidyl-peptidase 3 (DPP-3) (an exopeptidase) * * * Omapatrilat - also inhibits ACE * * * Phosphoramidon - inhibitor of neprilysin and thermolysin; also inhibits ECE * * * RB-101 - also inhibits aminopeptidase N (APN) (an exopeptidase) * * * Sampatrilat * * * Spinorphan - also inhibits APN, ACE, and DPP-3 * * * Tynorphin - also inhibits APN, ACE, and DPP-3 * Trypsin inhibitors/others * * Aloxistatin - inhibitor of cysteine proteases * * Camostat - inhibitor of trypsin and various other proteases * * Ecallantide - kallikrein inhibitor * * Leupeptin - non-selective inhibitor of cysteine, serine, and threonine proteases * * Nafamostat - inhibitor of trypsin, tryptase, and various other serine proteases * * Pacifastins - trypsin and chymotrypsin inhibitor * * Patamostat - trypsin inhibitor * * Pepstatin - inhibitor of renin and various aspartyl proteases * * Sepimostat - inhibitor of serine proteases * * Sivelestat - inhibitor of neutrophil elastase * * Talopeptin - inhibitor of thermolysin and other metalloproteases * * Ulinastatin - inhibitor of trypsin and various other proteases * * Upamostat - serine protease inhibitor * Renin inhibitors * * Aliskiren * * Ciprokiren * * Ditekiren * * Enalkiren * * Pepstatin * * Remikiren * * Terlakiren * * Zankiren 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Endopeptidase inhibitor」の詳細全文を読む スポンサード リンク
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